« Previous
Next »
Nutrition
Volume 27, Issue 1
, Pages 81-85
, January 2011
Neonatal exposure to sucralose does not alter biochemical markers of neuronal development or adult behavior
References
- . Sucralose—a new artificial sweetener. Med Lett Drugs Ther. 1998;40(1030):67–68
- . Food additives permitted for direct addition to food for human consumption: sucralose. 21CFR17263. 1998;
- . Food additives permitted for direct addition to food for human consumption: sucralose. 21CFR17264. 1999;
- . Artificial sweeteners: no calories.sweet!. FDA Consumer Mag. 2006;40:27–28
- . Sucralose and migraine. Headache. 2008;48(1):164–165
- . The pharmacokinetics and metabolism of sucralose in the mouse. Food Chem Toxicol. 2000;38(suppl 2):S107–S110
- . The pharmacokinetics and metabolism of sucralose in the rabbit. Food Chem Toxicol. 2000;38(suppl 2):S111–S113
- . The pharmacokinetics and metabolism of sucralose in the dog. Food Chem Toxicol. 2000;38(suppl 2):S99–106
- . The metabolic fate of sucralose in rats. Food Chem Toxicol. 2000;38(suppl 2):S115–S121
- . A combined chronic toxicity/carcinogenicity study of sucralose in Sprague-Dawley rats. Food Chem Toxicol. 2000;38(suppl 2):S71–S89
- . Sucralose—an overview of the toxicity data. Food Chem Toxicol. 2000;38(suppl 2):S1–S6
- . Sucralose metabolism and pharmacokinetics in man. Food Chem Toxicol. 2000;38(suppl 2):S31–S41
- . Artificial sweetener persists in the environment. Environ Sci Technol. 2008;42(9):3125
- Brorström-Lundén E, Svensson A, Viktor T, Woldegiorgis A, Remberger M, Kaj L, et al. Measurements of Sucralose in the Swedish Screening Program 2007, Part I; Sucralose in surface waters and STP samples. IVL Swedish Environmental Research Institute, 2007.
- . The intake of intense sweeteners—an update review. Food Addit Contam. 2006;23(4):327–338
- . Applied neurochemistry. Oxford: Blackwell; 1968;p. 178–221, 253–316
- . Comparative aspects of the brain growth spurt. Early Hum Dev. 1979;3(1):79–83
- . Neonatal exposure to PFOS and PFOA in mice results in changes in proteins which are important for neuronal growth and synaptogenesis in the developing brain. Toxicol Sci. 2009;108(2):412–418
- . Neonatal ontogeny and neurotoxic effect of decabrominated diphenyl ether (PBDE 209) on levels of synaptophysin and tau. Int J Dev Neurosci. 2009;27(5):423–429
- . Exposure to polybrominated diphenyl ethers 203 and 206 during the neonatal brain growth spurt affects proteins important for normal neurodevelopment in mice. Toxicol Sci. 2009;109(2):306–311
- . Neonatal exposure to decabrominated diphenyl ether (PBDE 209) results in changes in BDNF, CaMKII and GAP-43, biochemical substrates of neuronal survival, growth, and synaptogenesis. Neurotoxicology. 2008;29(1):152–159
- . Neonatal ketamine exposure results in changes in biochemical substrates of neuronal growth and synaptogenesis, and alters adult behavior irreversibly. Toxicology. 2008;249(2–3):153–159
- . Brominated flame retardants: a novel class of developmental neurotoxicants in our environment?. Environ Health Perspect. 2001;109(9):903–908
- . Neonatal exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) causes neurobehavioural defects in adult mice. Neurotoxicology. 2008;29(1):160–169
- . Neurobehavioral derangements in adult mice receiving decabrominated diphenyl ether (PBDE 209) during a defined period of neonatal brain development. Toxicol Sci. 2003;76(1):112–120
- . Regional distribution of type II Ca2+/calmodulin-dependent protein kinase in rat brain. J Neurosci. 1985;5(12):3270–3277
- . Alpha-CaMKII–dependent plasticity in the cortex is required for permanent memory. Nature. 2001;411(6835):309–313
- . B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system. Prog Neurobiol. 1997;53(6):627–686
- . CaMKII regulates the density of central glutamatergic synapses in vivo. Nature. 1999;402(6758):195–199
- . Synaptophysin immunocytochemistry with thermal intensification: a marker of terminal axonal maturation in the human fetal nervous system. Brain Dev. 1999;21(1):41–50
- . Synaptophysin: leading actor or walk-on role in synaptic vesicle exocytosis?. Bioessays. 2004;26(4):445–453
- . Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog Neurobiol. 2008;85(2):148–175
- . Neonatal ontogeny and neurotoxic effect of decabrominated diphenyl ether (PBDE 209) on levels of synaptophysin and tau. Int J Dev Neurosci. 2009;27(5):423–429
- . Behavioral deficits associated with fetal alcohol exposure are reversed by prenatal thyroid hormone treatment: a role for maternal thyroid hormone deficiency in FAE. Mol Psychiatry. 2005;10(10):961–971
- . Exposure to DDT during a defined period in neonatal life induces permanent changes in brain muscarinic receptors and behaviour in adult mice. Brain Res. 1992;582(2):277–281
- . MPTP-induced behavioural deficits in mice: validity and utility of a model of Parkinsonism (PhD thesis). Uppsala: Uppsala University; 1994;
- . Procedures for the behavioural science. Belmont, CA: Brooks/Cole; 1968;
- . A brominated flame retardant, 2,2′,4,4′,5-pentabromodiphenyl ether: uptake, retention, and induction of neurobehavioral alterations in mice during a critical phase of neonatal brain development. Toxicol Sci. 2002;67(1):98–103
- . Neonatal exposure to polybrominated diphenyl ether (PBDE 153) disrupts spontaneous behaviour, impairs learning and memory, and decreases hippocampal cholinergic receptors in adult mice. Toxicol Appl Pharmacol. 2003;192(2):95–106
- . Neonatal exposure to higher brominated diphenyl ethers, hepta-, octa-, or nonabromodiphenyl ether, impairs spontaneous behavior and learning and memory functions of adult mice. Toxicol Sci. 2006;92(1):211–218
- . Physicochemical properties of the sweetener sucralose. J Food Sci. 1989;54(6):1646–1649
- . Acute exposure of the neonatal rat to triethyltin results in persistent changes in neurotypic and gliotypic proteins. J Pharmacol Exp Ther. 1988;244(1):368–378
- . Acute exposure of the neonatal rat to tributyltin results in decreases in biochemical indicators of synaptogenesis and myelinogenesis. J Pharmacol Exp Ther. 1988;246(1):394–402
- . Developmental profiles of synaptophysin in granule cells of rat cerebellum: an immunohistocytochemical study. J Electron Microsc (Tokyo). 1996;45(3):185–194
- Neonatal exposure to brominated flame retardant BDE-47 reduces long-term potentiation and postsynaptic protein levels in mouse hippocampus. Environ Health Perspect. 2007;115(6):865–870
- Effects of hypothyroidism induced by perinatal exposure to PTU on rat behavior and synaptic gene expression. Toxicology. 2005;212(2–3):135–147
- . Adaptation and habituation to an open field and responses to various stressful events in animals with neonatal lesions in the amygdala or ventral hippocampus. Brain Res. 2001;918(1–2):153–165
- . Effects of novelty and habituation on acetylcholine, GABA, and glutamate release from the frontal cortex and hippocampus of freely moving rats. Neuroscience. 2001;106(1):43–53
This work was supported by grants from Formas, the Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning.
PII: S0899-9007(09)00431-6
doi: 10.1016/j.nut.2009.10.007
© 2011 Elsevier Inc. All rights reserved.
« Previous
Next »
Nutrition
Volume 27, Issue 1
, Pages 81-85
, January 2011
