Nutrition
Volume 22, Issue 10 , Pages 1057-1066 , October 2006

Calcium nutrition and metabolism during infancy

Received 20 December 2005 ,Accepted 23 May 2006.

References 

  1. Chan G. Calcium and bone mineral status in infant’s and children’s nutrition. 2nd ed. New York: Raven Press; 1989;
  2. Steichen JJ, Gratton TL, Tsang RC. Osteopenia of prematurity: the cause and possible treatment. J Pediatr. 1980;96(pt 2):528–534
  3. Felderbauer P, Hoffmann P, Klein W, Bulut K, Ansorge N, Epplen JT, et al. Identification of a novel calcium-sensing receptor gene mutation causing familial hypocalciuric hypercalcemia by single-strand conformation polymorphism analysis. Exp Clin Endocrinol Diabetes. 2005;113:31–34
  4. Evans KN, Bulmer JN, Kilby MD, Hewison M. Vitamin D and placental-decidual function. J Soc Gynecol Investig. 2004;11:263–271
  5. Loughead JL, Mimouni F, Tsang RC. Serum ionized calcium concentrations in normal neonates. Am J Dis Child. 1988;142:516–518
  6. Wandrup J, Kroner J, Pryds O, Kastrup KW. Age-related reference values for ionized calcium in the first week of life in premature and full-term neonates. Scand J Clin Lab Invest. 1988;48:255–260
  7. Nemeth EF. Regulation of cytosolic calcium by extracellular divalent cations in C-cells and parathyroid cells. Cell Calcium. 1990;11:323–327
  8. Brown EM. Extracellular Ca2+ sensing, regulation of parathyroid cell function, and role of Ca2+ and other ions as extracellular (first) messengers. Physiol Rev. 1991;71:371–411
  9. Speer G, Toth M, Niller HH, Salamon D, Takacs I, Miheller P, et al. Calcium metabolism and endocrine functions in a family with familial hypocalciuric hypercalcemia. Exp Clin Endocrinol Diabetes. 2003;111:486–490
  10. Lam CW, Lee KF, Chan AO, Poon PM, Law TY, Tong SF. Novel missense mutation in the CASR gene in a Chinese family with familial hypocalciuric hypercalcemia. Clin Chim Acta. 2005;360:167–172
  11. Venkataraman PS, Blick KE, Fry HD, Rao RK. Postnatal changes in calcium-regulating hormones in very-low-birth-weight infants (Effect of early neonatal hypocalcemia and intravenous calcium infusion on serum parathyroid hormone and calcitonin homeostasis). Am J Dis Child. 1985;139:913–916
  12. Venkataraman PS, Tsang RC, Steichen JJ, Grey I, Neylan M, Fleischman AR. Early neonatal hypocalcemia in extremely preterm infants (High incidence, early onset, and refractoriness to supraphysiologic doses of calcitriol). Am J Dis Child. 1986;140:1004–1008
  13. Chan GM, Tsang RC, Chen IW, DeLuca HF, Steichen JJ. The effect of 1,25(OH)2 vitamin D3 supplementation in premature infants. J Pediatr. 1978;93:91–96
  14. Fraser DR. Regulation of the metabolism of vitamin D. Physiol Rev. 1980;60:551–613
  15. Colette C, Monnier L, Pares Herbute N, Blotman F, Mirouze J. Calcium absorption in corticoid treated subjects effects of a single oral dose of calcitriol. Horm Metab Res. 1987;19:335–338
  16. Namgung R, Tsang RC, Specker BL, Sierra RI, Ho ML. Reduced serum osteocalcin and 1,25-dihydroxyvitamin D concentrations and low bone mineral content in small for gestational age infants: evidence of decreased bone formation rates. J Pediatr. 1993;122:269–275
  17. Favus MJ, Tembe V. The use of pharmacologic agents to study mechanisms of intestinal calcium transport. J Nutr. 1992;122(suppl):683–686
  18. Brommage R, Neuman WF. Mechanism of mobilization of bone mineral by 1,25-dihydroxyvitamin D3. Am J Physiol. 1979;237:E113–E120
  19. Raisz LG, Trummel CL, Holick MF, DeLuca HF. 1,25-dihydroxycholecalciferol: a potent stimulator of bone resorption in tissue culture. Science. 1972;175:768–769
  20. Abrams SA, Esteban NV, Vieira NE, Yergey AL. Dual tracer stable isotopic assessment of calcium absorption and endogenous fecal excretion in low birth weight infants. Pediatr Res. 1991;29:615–618
  21. Hillman LS, Johnson LS, Lee DZ, Vieira NE, Yergey AL. Measurement of true absorption, endogenous fecal excretion, urinary excretion, and retention of calcium in term infants by using a dual-tracer, stable-isotope method. J Pediatr. 1993;123:444–456
  22. Specker BL, Beck A, Kalkwarf H, Ho M. Randomized trial of varying mineral intake on total body bone mineral accretion during the first year of life. Pediatrics. 1997;99:E12
  23. Bronner F. Current concepts of calcium absorption: an overview. J Nutr. 1992;122(suppl):641–643
  24. Lacour B, Tardivel S, Drueke T. Stimulation by citric acid of calcium and phosphorus bioavailability in rats fed a calcium-rich diet. Miner Electrolyte Metab. 1997;23:79–87
  25. Hansen M, Sandstrom B, Jensen M, Sorensen SS. Casein phosphopeptides improve zinc and calcium absorption from rice-based but not from whole-grain infant cereal. J Pediatr Gastroenterol Nutr. 1997;24:56–62
  26. Pansu D, Duflos C, Bellaton C, Bronner F. Solubility and intestinal transit time limit calcium absorption in rats. J Nutr. 1993;123:1396–1404
  27. Schanler RJ, Abrams SA. Postnatal attainment of intrauterine macromineral accretion rates in low birth weight infants fed fortified human milk. J Pediatr. 1995;126:441–447
  28. Lifschitz CH, Abrams SA. Addition of rice cereal to formula does not impair mineral bioavailability. J Pediatr Gastroenterol Nutr. 1998;26:175–178
  29. Sandstrom B, Cederblad A, Kivisto B, Stenquist B, Andersson H. Retention of zinc and calcium from the human colon. Am J Clin Nutr. 1986;44:501–504
  30. Halbert KETR. Neonatal calcium, phosphorus, and magnesium homeostasis. Philadelphia: WB Saunders; 1992;
  31. Chan GM. Growth and bone mineral status of discharged very low birth weight infants fed different formulas or human milk. J Pediatr. 1993;123:439–443
  32. Bishop NJ, King FJ, Lucas A. Increased bone mineral content of preterm infants fed with a nutrient enriched formula after discharge from hospital. Arch Dis Child. 1993;68(5 Spec No):573–578
  33. Lucas A, Bishop NJ, King FJ, Cole TJ. Randomised trial of nutrition for preterm infants after discharge. Arch Dis Child. 1992;67:324–327
  34. In:  Kleinman RE editors. Pediatric nutrition handbook. 5th ed. Elk Grove, IL: American Academy of Pediatrics; 2004;2003–2004 CoN
  35. Carver JD, Wu PY, Hall RT, Ziegler EE, Sosa R, Jacobs J, et al. Growth of preterm infants fed nutrient-enriched or term formula after hospital discharge. Pediatrics. 2001;107:683–689
  36. Reis BB, Hall RT, Schanler RJ, Berseth CL, Chan G, Ernst JA, et al. Enhanced growth of preterm infants fed a new powdered human milk fortifier: a randomized, controlled trial. Pediatrics. 2000;106:581–588
  37. Schanler RJ, Abrams SA, Garza C. Bioavailability of calcium and phosphorus in human milk fortifiers and formula for very low birth weight infants. J Pediatr. 1988;113(pt 1):95–100
  38. Stathos TH, Shulman RJ, Schanler RJ, Abrams SA. Effect of carbohydrates on calcium absorption in premature infants. Pediatr Res. 1996;39(pt 1):666–670
  39. Abrams SA, Griffin IJ, Davila PM. Calcium and zinc absorption from lactose-containing and lactose-free infant formulas. Am J Clin Nutr. 2002;76:442–446
  40. Lidestri M, Agosti M, Marini A, Boehm G. Oligosaccharides might stimulate calcium absorption in formula-fed preterm infants. Acta Paediatr Suppl. 2003;91(441):91–92
  41. Bosscher D, Van Caillie-Bertrand M, Van Dyck K, Robberecht H, Van Cauwenbergh R, Deelstra H. Thickening infant formula with digestible and indigestible carbohydrate: availability of calcium, iron, and zinc in vitro. J Pediatr Gastroenterol Nutr. 2000;30:373–378
  42. Bosscher D, Van Caillie-Bertrand M, Van Cauwenbergh R, Deelstra H. Availabilities of calcium, iron, and zinc from dairy infant formulas is affected by soluble dietary fibers and modified starch fractions. Nutrition. 2003;19:641–645
  43. Gee JM, Lee-Finglas WE, Wortley GM, Pell JD, Johnson IT. Influence of non-starch polysaccharides on gastrointestinal endocrine mechanisms. Eur J Clin Nutr. 1995;49(suppl 3):S170–S172
  44. Southon S, Gee JM, Johnson IT. The effect of dietary protein source and guar gum on gastrointestinal growth and enteroglucagon secretion in the rat. Br J Nutr. 1987;58:65–72
  45. Fuessl HS, Williams G, Adrian TE, Bloom SR. Guar sprinkled on food: effect on glycaemic control, plasma lipids and gut hormones in non–insulin dependent diabetic patients. Diabet Med. 1987;4:463–468
  46. Johnson IT, Gee JM. Inhibitory effect of guar gum on the intestinal absorption of glucose in vitro. Proc Nutr Soc. 1980;39:52A
  47. Johnson IT, Gee JM. Gastrointestinal adaptation in response to soluble non-available polysaccharides in the rat. Br J Nutr. 1986;55:497–505
  48. Harmuth-Hoene AE, Meier-Ploeger A, Leitzmann C. [Effect of carob bean flour on the resorption of minerals and trace elements in man] Z Ernahrungswiss. 1982;21:202–213
  49. Aggett PJ, Agostoni C, Goulet O, Hernell O, Koletzko B, Lafeber HL, et al. Antireflux or antiregurgitation milk products for infants and young children: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2002;34:496–498
  50. Erba D, Ciappellano S, Testolin G. Effect of the ratio of casein phosphopeptides to calcium (w/w) on passive calcium transport in the distal small intestine of rats. Nutrition. 2002;18:743–746
  51. Naude SP, Prinsloo JG, Haupt CE. Comparison between a humanized cow’s milk and a soy product for premature infants. S Afr Med J. 1979;55:982–986
  52. Heaney RP, Weaver CM, Fitzsimmons ML. Soybean phytate content: effect on calcium absorption. Am J Clin Nutr. 1991;53:745–747
  53. Allen LH. Calcium bioavailability and absorption: a review. Am J Clin Nutr. 1982;35:783–808
  54. Kohler L, Meeuwisse G, Mortensson W. Food intake and growth of infants between six and twenty-six weeks of age on breast milk, cow’s milk formula, or soy formula. Acta Paediatr Scand. 1984;73:40–48
  55. Cherry FF, Cooper MD, Stewart RA, Platou RV. Cow versus soy formulas (Comparative evaluation in normal infants). Am J Dis Child. 1968;115:677–692
  56. Kulkarni PB, Dorand RD, Bridger WM, Payne JH, Montiel DC, Hill JG. Rickets in premature infants fed different formulas. South Med J. 1984;77:13–1620
  57. Chan GM, Leeper L, Book LS. Effects of soy formulas on mineral metabolism in term infants. Am J Dis Child. 1987;141:527–530
  58. Chan GM, Mileur L, Hansen JW. Calcium and phosphorus requirements in bone mineralization of preterm infants. J Pediatr. 1988;113(pt 2):225–229
  59. Committee on Nutrition of the Preterm Infant, European Society of Paediatric Gastroenterology and Nutrition (ESPAN). Nutrition and feeding of preterm infants. Oxford, England: Blackwell Scientific Publications; 1987;
  60. Lee DB, Hu MS, Kayne LH, Nakhoul F, Jamgotchian N. The importance of non-vitamin D–mediated calcium absorption. Contrib Nephrol. 1991;91:14–20
  61. Sulkers EJ, Lafeber HN, Degenhart HJ, Lindemans J, Sauer PJ. Comparison of two preterm formulas with or without addition of medium-chain triglycerides (MCTs) (II: Effects on mineral balance). J Pediatr Gastroenterol Nutr. 1992;15:42–47
  62. Lucas A, Quinlan P, Abrams S, Ryan S, Meah S, Lucas PJ. Randomised controlled trial of a synthetic triglyceride milk formula for preterm infants. Arch Dis Child Fetal Neonatal Ed. 1997;77:F178–F184
  63. Kennedy K, Fewtrell MS, Morley R, Abbott R, Quinlan PT, Wells JC, et al. Double-blind, randomized trial of a synthetic triacylglycerol in formula-fed term infants: effects on stool biochemistry, stool characteristics, and bone mineralization. Am J Clin Nutr. 1999;70:920–927
  64. Neville MC, Allen JC, Archer PC, Casey CE, Seacat J, Keller RP, et al. Studies in human lactation: milk volume and nutrient composition during weaning and lactogenesis. Am J Clin Nutr. 1991;54:81–92
  65. Koo WW, Hammami M, Margeson DP, Nwaesei C, Montalto MB, Lasekan JB. Reduced bone mineralization in infants fed palm olein-containing formula: a randomized, double-blinded, prospective trial. Pediatrics. 2003;111(pt 1):1017–1023
  66. Carnielli VP, Luijendijk IH, van Goudoever JB, Sulkers EJ, Boerlage AA, Degenhart HJ, et al. Feeding premature newborn infants palmitic acid in amounts and stereoisomeric position similar to that of human milk: effects on fat and mineral balance. Am J Clin Nutr. 1995;61:1037–1042
  67. Antonson DYR, Heires P, Murray N, Merkel K, Ferguson P, Moore T. Effect of neonatal and infant feeding on bone density at 4 years. In: Section on perinatal pediatrics; October 10, 2004. San Francisco: Journal of Perinatology; 2004;p. 571–609
  68. Dewey KG, Finley DA, Lonnerdal B. Breast milk volume and composition during late lactation (7–20 months). J Pediatr Gastroenterol Nutr. 1984;3:713–720
  69. Chan GM. Human milk calcium and phosphate levels of mothers delivering term and preterm infants. J Pediatr Gastroenterol Nutr. 1982;1:201–205
  70. Abrams SA, Grusak MA, Stuff J, O’Brien KO. Calcium and magnesium balance in 9–14-y-old children. Am J Clin Nutr. 1997;66:1172–1177
  71. Masel JP, Tudehope D, Cartwright D, Cleghorn G. Osteopenia and rickets in the extremely low birth weight infant–a survey of the incidence and a radiological classification. Australas Radiol. 1982;26:83–96
  72. Backstrom MC, Kouri T, Kuusela AL, Sievanen H, Koivisto AM, Ikonen RS, et al. Bone isoenzyme of serum alkaline phosphatase and serum inorganic phosphate in metabolic bone disease of prematurity. Acta Paediatr. 2000;89:867–873
  73. Lucas A, Brooke OG, Baker BA, Bishop N, Morley R. High alkaline phosphatase activity and growth in preterm neonates. Arch Dis Child. 1989;64(7 Spec No):902–909
  74. Faerk J, Peitersen B, Petersen S, Michaelsen KF. Bone mineralisation in premature infants cannot be predicted from serum alkaline phosphatase or serum phosphate. Arch Dis Child Fetal Neonatal Ed. 2002;87:F133–F136
  75. Bishop N. Bone disease in preterm infants. Arch Dis Child. 1989;64(10 Spec No):1403–1409
  76. Senterre J, Salle B. Renal aspects of calcium and phosphorus metabolism in preterm infants. Biol Neonate. 1988;53:220–229
  77. Karlen J, Aperia A, Zetterstrom R. Renal excretion of calcium and phosphate in preterm and term infants. J Pediatr. 1985;106:814–819
  78. Catache M, Leone CR. Role of plasma and urinary calcium and phosphorus measurements in early detection of phosphorus deficiency in very low birthweight infants. Acta Paediatr. 2003;92:76–80
  79. Pohlandt F. Prevention of postnatal bone demineralization in very low-birth-weight infants by individually monitored supplementation with calcium and phosphorus. Pediatr Res. 1994;35:125–129
  80. Kruger DM, Lyne ED, Kleerekoper M. Vitamin D deficiency rickets. A report on three cases. Clin Orthop Relat Res. 1987;224:277–283
  81. Greer FR. Issues in establishing vitamin D recommendations for infants and children. Am J Clin Nutr. 2004;80(suppl):1759S–1762S
  82. Koo WW, Gupta JM, Nayanar VV, Wilkinson M, Posen S. Skeletal changes in preterm infants. Arch Dis Child. 1982;57:447–452
  83. Johnson CB. Neonatal rickets: metabolic bone disease of prematurity. Neonatal Netw. 1991;9:13–17
  84. Gartner LM, Greer FR. Prevention of rickets and vitamin D deficiency: new guidelines for vitamin D intake. Pediatrics. 2003;111(pt 1):908–910
  85. Fewtrell MS, Prentice A, Jones SC, Bishop NJ, Stirling D, Buffenstein R, et al. Bone mineralization and turnover in preterm infants at 8–12 years of age: the effect of early diet. J Bone Miner Res. 1999;14:810–820
  86. Fewtrell MS, Cole TJ, Bishop NJ, Lucas A. Neonatal factors predicting childhood height in preterm infants: evidence for a persisting effect of early metabolic bone disease?. J Pediatr. 2000;137:668–673
  87. Abrams SA, Schanler RJ, Yergey AL, Vieira NE, Bronner F. Compartmental analysis of calcium metabolism in very-low-birth-weight infants. Pediatr Res. 1994;36:424–428
  88. Widdowson EMDJ. Chemical composition of the body. Orlando: Academic Press; 1964;
  89. Kelly HJ, Sloan RE, Hoffman W, Saunders C. Accumulation of nitrogen and six minerals in the human fetus during gestation. Hum Biol. 1951;23:61–74

PII: S0899-9007(06)00234-6

doi: 10.1016/j.nut.2006.05.014

Nutrition
Volume 22, Issue 10 , Pages 1057-1066 , October 2006