Patients with severe bowel malabsorption do not have changes in iodine status

Navarro, Anderson Marilere; Suen, Vivian Marques Miguel; Souza, Isabel Machado; De Oliveira, José Eduardo Dutra; Marchini, Julio Sergio

doi:10.1016/j.nut.2005.02.006

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Volume 21, Issue 9 , Pages 895-900, September 2005

Patients with severe bowel malabsorption do not have changes in iodine status

Anderson Marilere Navarro, M.Nutr.S.
- Division of Clinical Nutrition, Department of Clinical Medicine, Medical School of Ribeirão Preto, University of São Paulo, São Paulo, Brazil
- Corresponding author. Tel.: +55-16-602-3187; fax: +55-16-633-6695.
Vivian Marques Miguel Suen, Ph.D.
- Division of Clinical Nutrition, Department of Clinical Medicine, Medical School of Ribeirão Preto, University of São Paulo, São Paulo, Brazil
Isabel Machado Souza, Pharm.G.
- Pediatrics Laboratory, University Hospital, Medical School of Ribeirão Preto, University of São Paulo, Ribeirao Preto, São Paulo, Brazil
José Eduardo Dutra De Oliveira, Ph.D.
- Division of Clinical Nutrition, Department of Clinical Medicine, Medical School of Ribeirão Preto, University of São Paulo, São Paulo, Brazil
Julio Sergio Marchini, Ph.D.
- Division of Clinical Nutrition, Department of Clinical Medicine, Medical School of Ribeirão Preto, University of São Paulo, São Paulo, Brazil

Received 7 November 2004; accepted 5 February 2005. published online 27 June 2005.

Abstract

Objective

We evaluated the influence of intestinal malabsorption on iodine status in patients who had short gut syndrome and received total parenteral nutrition (group I) compared with control subjects who had eutrophia (group II) and patients who had other illnesses but normal digestive tracts (group III).

Methods

Twenty-seven subjects were studied. Iodine intake was determined by the measurement of iodine in ingested food and in parenteral nutrition solutions. Urinary iodine excretion was measured by the Sandell-Kalthoff reaction. Urinary creatinine, anthropometric, and thyroid hormone functions were also determined.

Results

Daily iodine intakes were 658 ± 125 (mean ± standard deviation), 573 ± 204, and 629 ± 208 μg for groups I, II, and III, respectively. Daily urinary iodine excretion levels were 399 ± 308, 439 ± 192, and 370 ± 268 μg and ratios of urinary iodine (micrograms) to creatinine (grams) were 614 ± 349, 354 ± 142, and 483 ± 292, respectively. There were no statistically significant differences across groups.