Nutrition
Volume 21, Issue 9 , Pages 920-924 , September 2005

Melatonin in walnuts: Influence on levels of melatonin and total antioxidant capacity of blood

Received 15 November 2004 ,Accepted 4 February 2005.

References 

  1. Feldman EB . The scientific evidence for a beneficial health relationship between walnuts and coronary heart disease . J Nutr . 2002;132:1062S–1101S
  2. Iwamoto M, Imaizumi K, Sato M, Hirooka Y, Sakai K, Takeshita A, et al. Serum lipid profiles in Japanese women and men during consumption of walnuts . Eur J Clin Nutr . 2002;56:629–637
  3. Ros E, Nunez I, Perez-Heras A, Serra M, Gilabert R, Casals E, et al. A walnut diet improves endothelial function in hypercholesterolemic subjects (a randomized crossover trial) . Circulation . 2004;109:1609–1614
  4. Kris-Etherton PM , Yu-Poth S , Sabate J , Ratcliffe HE , Zhao G , Etherton TD . Nuts and their bioactive constituents (effects on serum lipids and other factors that affect disease risk) . Am J Clin Nutr . 1999;70:504S–511S
  5. Amaral JS , Casal S , Pereira JA , Seabra RM , Oliveira BP . Determination of sterol and fatty acid composition, oxidative stability and nutritional value of six walnuts (Juglan regia L) cultivars grown in Portugal . J Agric Food Sci . 2003;51:6698–6702
  6. Maguire LS , O’Sullivan SM , Galvin K , O’Connor TP , O’Brien NM . Fatty acid profile, tocopherol, squalene and phytosterol content of walnuts, almonds, peanuts, hazelnuts and the macadamia nut . Int J Food Sci Nutr . 2004;55:171–178
  7. Anderson KJ , Teuber SS , Gobeille A , Cremin P , Waterhouse AL , Steinberg FM . Walnut polyphenolics inhibit in vitro human plasma and LDL oxidation . J Nutr . 2001;131:2837–2842
  8. Sabate J . Nut consumption and body weight . Am J Clin Nutr . 2003;78:647S–650S
  9. Reiter RJ , Tan DX . Melatonin (a novel protective agent against oxidative injury of ischemic/reperfused heart) . Cardiovasc Res . 2003;58:10–19
  10. Sahna E , Parlakspinar H , Ozer MK , Ozturk F , Ozugurlu F , Acet A . Melatonin protects against myocardial doxorubicin toxicity in rats (role of physiological concentrations) . J Pineal Res . 2003;35:257–261
  11. Hattori A , Migitaka H , Iigo M , Itoh M , Yamamoto K , Ohtani-Kandro R , et al.   Identification of melatonin in plants and its effect on plasma melatonin levels and binding to melatonin receptors in vertebrates . Biochem Mol Biol Int . 1995;35:627–634
  12. Reiter RJ , Tan DX , Burkhardt S , Manchester LC . Melatonin in plants . Nutr Rev . 2001;59:286–290
  13. Reiter RJ . Pineal melatonin (cell biology of its synthesis and of its physiological interactions) . Endocr Rev . 1991;12:151–180
  14. Hardeland R , Poeggeler B . Non-vertebrate melatonin . J Pineal Res . 2003;34:233–241
  15. Fraser S , Cowen P , Franklin M , Franey C , Arendt J . Direct radioimmunoassay of melatonin in plasma . Clin Chem . 1983;29:1703–1704
  16. Webley GE , Mehl H , Willey KP . Validation of a sensitive direct assay for melatonin for investigation of circadian rhythms in different species . J Endocrinol . 1985;106:387–394
  17. Re R , Pellegrini N , Proteggente A , Panala A , Yang M , Rice-Evans C . Antioxidant activity applying an improved ABTS radical cation decolorization assay . Free Radic Biol Med . 1999;26:1231–1237
  18. Benzie IFF , Strain JJ . The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power” (the FRAP assay) . Anal Biochem . 1996;239;: 70–60
  19. Dubbels R , Reiter RJ , Klenke E , Goebel A , Schnakenberg E , Ehlers C , et al.   Melatonin in edible plants identified by radioimmunoassay and by high performance liquid chromatography-mass spectrometry . J Pineal Res . 1995;18:28–31
  20. Murch SJ , Simmons CB , Saxena PK . Melatonin in feverfew and other medicinal plants . Lancet . 1997;350:1598–1599
  21. Badria FA . Melatonin, serotonin, and tryptamine in some Egyptian food and medicinal plants . J Med Food . 2002;5:153–157
  22. Chen G , Huo Y , Tan DX , Liang Z , Zhang W , Zhang Y . Melatonin in Chinese herbal medicines . Life Sci . 2003;73:19–26
  23. Tan DX , Chen LD , Poeggeler B , Manchester LC , Reiter RJ . Melatonin (a potent, endogenous hydroxyl radical scavenger) . Endocr J . 1993;1:57–60
  24. Allegra M , Reiter RJ , Tan DX , Gentile C , Tesoriere L , Livrea MA . The chemistry of melatonin’s interaction with reactive species . J Pineal Res . 2003;34:1–10
  25. Tan DX, Manchester LC, Hardeland R, Lopez-Barillo S, Mayo JC, Sainz RM, et al. Melatonin (a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin) . J Pineal Res . 2003;34:75–78
  26. Manchester LC , Tan DX , Reiter RJ , Park W , Monis K , Qi W . High levels of melatonin in the seeds of edible plants (possible function in germ cell protection) . Life Sci . 2000;67:3023–3029
  27. Kolar J , Johnson CH , Machackova I . Presence and possible role of melatonin in a short-day flowering plant, Chenopodium rubrum . Adv Exp Med Biol . 1999;460:391–393
  28. Rosales-Corral S, Tan DX, Reiter RJ, Valdivia-Velazquez M, Martinez-Barboza C, Acosta-Martinez JP, et al. Orally administered melatonin reduces oxidative stress and proinflammatory cytokines induced by amyloid-beta peptide in rat brain (a comparative in vivo study versus vitamin C and E) . J Pineal Res . 2003;35:80–84
  29. Sharman EH , Sharman KG , Ge YW , Lahiri K , Bondy SC . Age-related changes in murine CNS mRNA gene expression are modulated by dietary melatonin . J Pineal Res . 2004;36:165–170
  30. Benot S , Molinero P , Soutto M , Goberna R , Guerrero JM . Circadian variations in the rat total antioxidant status (correlation with melatonin levels) . J Pineal Res . 1998;25:1–4
  31. Benot S , Goberna R , Reiter RJ , Garcia-Maurino S , Osuna C , Guerrero JM . Physiological levels of melatonin contribute to the antioxidant capacity of human serum . J Pineal Res . 1999;27:59–64
  32. Morreale M , Livrea MA . Synergistic effect of glycolic acid on the antioxidant activity of alpha-tocopherol and melatonin in lipid bilayers and in human skin homogenates . Biochem Mol Biol Int . 1997;42:1093–1102
  33. Gitto E , Tan DX , Reiter RJ , Karbownik M , Manchester LC , Cuzzocrea S , et al.   Individual and synergistic actions of melatonin (studies with vitamin E, vitamin C, glutathione and desferrioxamine (deferoxamine) in rat liver homogenates) . J Pharm Pharmacol . 2001;53:1393–1401
  34. Lopez-Burillo S , Tan DX , Mayo JC , Sainz RM , Manchester LC , Reiter RJ . Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents (a study of their individual and synergistic effects) . J Pineal Res . 2003;34:269–277
  35. Qi W, Reiter RJ, Tan DX, Garcia JJ, Manchester LC, Karbownik M, et al. Chromium (III) induced 8-hydroxydeoxyguanosine in DNA and its reduction by antioxidants (comparative effects of melatonin, ascorbate and vitamin E) . Environ Health Perspect . 2000;108:399–402
  36. Blask DE , Sauer LA , Dauchy RT . Melatonin as a chronobiotic/anticancer agent (cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy) . Curr Topics Med Chem . 2002;2:113–132
  37. Reiter RJ . Mechanism of cancer inhibition by melatonin . J Pineal Res . 2004;37:213–214
  38. Blask DE , Dauchy RT , Sauer LA , Krause JA . Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin (melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin) . Carcinogenesis . 2004;25:951–960
  39. Sauer LA , Dauchy RT , Blask DE . Polyunsaturated fatty acids, melatonin, and cancer prevention . Biochem Pharmacol . 2001;61:1455–1462

 This study was supported by a grant from the California Walnut Commission.

PII: S0899-9007(05)00163-2

doi: 10.1016/j.nut.2005.02.005

Nutrition
Volume 21, Issue 9 , Pages 920-924 , September 2005

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