Nutrition
Volume 18, Issue 7 , Pages 566-567 , July 2002

Effects of oral bovine colostrum supplementation on serum insulin-like growth factor-i levels

  • Harm Kuipers, MD, PhD

      Affiliations

    • Maastricht University, Maastricht, The Netherlands
    • Numico Research, Wageningen, The Netherlands
    • Corresponding Author InformationCorrespondence to: Harm Kuipers, MD, PhD, Department of Movement Sciences, PO Box 616, 6200 MD Maastricht, The Netherlands
    • ,
  • E van Breda, PhD

      Affiliations

    • Maastricht University, Maastricht, The Netherlands
    • Numico Research, Wageningen, The Netherlands
    • ,
  • G Verlaan, MSc

      Affiliations

    • Maastricht University, Maastricht, The Netherlands
    • Numico Research, Wageningen, The Netherlands
    • ,
  • R Smeets, PhD

      Affiliations

    • Maastricht University, Maastricht, The Netherlands
    • Numico Research, Wageningen, The Netherlands

References 

  1. Donovan SM, Odle J. Growth factors in milk as mediators of infant development. Ann Rev Nutr. 1994;14:147
  2. Schams D. Growth factors in milk. Endocr Regul. 1994;28:3
  3. Francis GL, et al.  Insulin-like growth factors 1 and 2 in bovine colostrum. Sequences and biological activities compared with those of a potent truncated form. Biochem J. 1988;251:95
  4. Tomas FM, Knowles SE, Owens PC, Read LC, Chandler CS, Gargoski SE, et al. Increased weight gain, nitrogen retention and muscle protein synthesis following treatment of diabetic rats with insulin-like growth factor (IGF)-1 and des(1–3)IGF-1. Biochem J. 1991;276:547
  5. Fryburg DA, Jahn LA, Hill SA, Oliveras DM, Barrett EJ. Insulin and insulin-like growth factor 1 enhance human skeletal muscle protein anabolism during hyperaminoacidemia by different mechanisms. J Clin Invest. 1995;96:1722
  6. Buckley J, Abbot M, Martin S, Brinkworth G, Whyte D. Effect of an oral bovine colostrum supplement (Intact™) on running performance. Proceedings of the Australian Conference of Science and Medicine in Sport. 1998;79:
  7. Buckley JD, Abbot MJ, Brinkworth GD, Whyte PBD. Bovine colostrum supplementation during training increases vertical jump performance (abstract). Pre-Olympic Congress on Sport Science, Sports Medicine and Physical Education, Brisbane, Australia. 2000;274
  8. Mero A, Miikkulainen H, Riski J, et al.  Effects of bovine colostrum supplementation on serum IGF-1, IgG, hormone, and saliva IgA during training. J Appl Physiol. 1997;83:1144
  9. Yarasheski KE. Growth hormone, effects on metabolism, body composition, muscle mass, and strength. In:  Holloszy JO editors. Exercise and sport sciences reviews. Vol 22:Baltimore: Williams & Wilkins; 1994;p. 285
  10. Souza SC, Frick GP, Wang X, et al.  A single arginine residue determines species specificity of the human growth hormone receptor. Proc Natl Acad Sci USA. 1995;92:959
  11. Haydar ZR, Blackman MR, Tobin JD, Wright JG, Fleg JL. The relationship between aerobic exercise capacity and circulating IGF-1 levels in healthy men and women. J Am Geriatr Soc. 2000;48:139

PII: S0899-9007(02)00800-6

Nutrition
Volume 18, Issue 7 , Pages 566-567 , July 2002

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